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CAS No. 252742-72-6, 3-(chloromethyl)-1,4-dihydro-1,2,4-triazol-5-one

  • 252742-72-6

  • C3H4ClN3O

  • 133.54

  • 1.83±0.1

  • 98% min

  • 199

  • 211.5

  • White or off-white powder

  • Antiretroviral; Antiemetics

  • Doravirine; Aprepitant; Fosaprepitant

  • 10/7/2031 (Doravirine); 9/18/2035 (Aprepitant); 1/11/2039 (Fosaprepitant)

  • Y

  • In Stock


Product Description

At Unibest, we offer the key intermediate, 3-(chloromethyl)-1,4-dihydro-1,2,4-triazol-5-one, under the CAS RN 252742-72-6. This compound plays a crucial role in the synthesis of the valuable antiretroviral medication, Doravirine, designed to combat HIV-1 infection, and two potent antiemetics - Aprepitant and Fosaprepitant, widely used in the management of nausea and vomiting induced by chemotherapy. It's noteworthy to mention that Fosaprepitant is a prodrug of Aprepitant.

We maintain rigorous standards for our products to ensure our pharmaceutical partners, including procurement managers, receive inhibitors of unsurpassed quality. Join us on our pathway to contribute to the betterment of human health through advanced solutions that really make a difference.

ROS for Doravirine

Doravirine Synthesis

To align with green chemistry, we have implemented the flow chemistry.

ROS for Aprepitant & Fosaprepitant

Aprepitant and Fosaprepitant Synthesis