252742-72-6
C3H4ClN3O
133.54
1.83±0.1
98% min
199
211.5
White or off-white powder
Antiretroviral; Antiemetics
Doravirine; Aprepitant; Fosaprepitant
10/7/2031 (Doravirine); 9/18/2035 (Aprepitant); 1/11/2039 (Fosaprepitant)
Y
In Stock
Availability: | |
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Product Description
At Unibest, we offer the key intermediate, 3-(chloromethyl)-1,4-dihydro-1,2,4-triazol-5-one, under the CAS RN 252742-72-6. This compound plays a crucial role in the synthesis of the valuable antiretroviral medication, Doravirine, designed to combat HIV-1 infection, and two potent antiemetics - Aprepitant and Fosaprepitant, widely used in the management of nausea and vomiting induced by chemotherapy. It's noteworthy to mention that Fosaprepitant is a prodrug of Aprepitant.
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ROS for Doravirine
To align with green chemistry, we have implemented the flow chemistry.
ROS for Aprepitant & Fosaprepitant