This product, CAS No. 3024622-70-3, is a key intermediate in the synthesis of TYK2 inhibitors R&D. It serves as an alternative backbone of potential TYK2 inhibitors, with another backbone being CAS No. 3024622-26-9. Below are the comparison of two scaffolds.

The synthetic route of CAS No. 3024622-70-3 (Backbone #2 in the above illustration) has been optimized by researchers at Unibest CDMO center with 4 fewer steps.

Reference

Pei, Z. et al. Kinase modulators and methods of use thereof. (2024).