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CAS No. 1357259-88-1

  • 1357259-88-1

  • C39H46N2O12

  • 734.8

  • 97% min (HPLC)

  • Anti-Neutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis

  • Avacopan

  • 5/29/2041 (Avacopan)

  • Complement 5a Receptor

  • N

  • 2019

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CAS No. 1357259-88-1

Product Description

This product, CAS No. 1357259-88-1, is an intermediate of Avacopan. It is the intermediate state to select the desired isomer of CAS No. 2969217-07-8, using (2R,3R)-2,3-Bis(4-methylphenoxy)butanedioic acid.


enantiomeric separation


CAS No. 2969217-07-8 is important for Avacopan API's chirality.



References

GYŰJTŐ, I. et al. Processes for preparation of avacopan and intermediates thereof. (2023).


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CAS No. 1357259-88-1 Avacopan intermediates