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CAS No. 838-57-3, ethyl 3-(4-nitrophenyl)-3-oxopropanoate

  • 838-57-3

  • C11H11NO5

  • 237.21

  • 1.3350

  • 98% min (HPLC)

  • 67-71

  • white crystalline powder

  • Anti-Neutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis

  • Avacopan

  • 5/29/2041 (Avacopan)

  • Complement 5a Receptor

  • N

  • 2020

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CAS No. 838-57-3, ethyl 3-(4-nitrophenyl)-3-oxopropanoate

Product Description

This product, CAS No. 838-57-3, is an intermediate of Avacopan. Unibest has supplied this product to a generic drug company giant in 2023.


CAS No. 838-57-3 is a starting material in the route described in Chemocentryx's patent. 



References


Fan, P. et al. PROCESSES AND INTERMEDIATES IN THE PREPARATION OF C5aR ANTAGONISTS. (2016).


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CAS No. 838-57-3 Avacopan intermediates