Product Detail

loading

Share to:
facebook sharing button
twitter sharing button
line sharing button
wechat sharing button
linkedin sharing button
pinterest sharing button
whatsapp sharing button
sharethis sharing button

Cas No. 35824-91-0, Daprodustat intermediate

  • 35824-91-0

  • C16H24N2O3

  • 292.37

  • 1.226±0.06

  • 98% min (HPLC)

  • 203

  • 172.9

  • White to off-white powder

  • Anemia

  • Daprodustat

  • 3/13/2038 (Daprodustat)

  • HIF prolyl hydroxylase

  • N

  • 200 kg Batch quantity

  • 2019

  • CDMO

Availability:
Inquire

Cas No. 35824-91-0, Daprodustat intermediate

Supply Chain

The Supply Chain Status in China

As of August 27, 2024, there are 37 potential suppliers manufacturing Daprodustat intermediate 1,3-Dicyclohexylbarbituric acid (CAS No. 35824-91-0), including 9 traders, 14 reagent distributors, 7 factories and 7 labs. Among factories and labs:

- The 25th percentile has an average registered capital of 1 million CNY;

- The 50th percentile has an average registerd capital of 5 million CNY;

-  The 75th percentile has an average registered capital of 14.58 million CNY.


Feeling overwhelmed? Contact Unibest if you need us to quality-check other sources to strengthen your supply chain or to find a tailored solution for your specific procurement request.

Usage and ROS Analysis


The Overall Synthesis Map of Daprodustat

Daprodustat ROS

This compound, 1,3-Dicyclohexylbarbituric acid, CAS No. 35824-91-0 is the essential intermediate of Daprodustat API synthesis. It is synthesized from 1,3-Dicyclohexylurea (CAS No. 2387-23-7) or 1,3-Dicyclohexylcarbodiimide (CAS No. 538-75-0).



References

1.    Wang, Y. & Ren, X. Substituted pyrimidinetrione compound, composition containing same and application of substituted pyrimidinetrione compound. (2018).
 
2.    Judge, T., Truglio, G. & Restelli, A. Method for Preparing and Purifying an Agent Suitable for Treating Anemia. (2023).
 
3.    Duffy, K. J. et al. Prolyl hydroxylase inhibitors. (2007).
 
4.    O’Brien, A. G., Ricci, E. M. & Journet, M. Dehydration of an Insoluble Urea Byproduct Enables the Condensation of DCC and Malonic Acid in Flow. Org. Process Res. Dev. 22, 399–402 (2018).
 
5.    Mao, Y., Xu, Z. & Zheng, J. Preparation method of dapinustat intermediate. (2024).


Previous: 
Next: 
Cas No. 35824-91-0 Daprodustat intermediate 1 3-Dicyclohexylbarbituric acid