Tirzepatide intermediate, P7, CAS No.2461524-70-7

Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It is a 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life. Tirzepatide selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1.

Tirzepatide enhances first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose dependent manner.

This Tirzepatide intermediate, CAS No. 2461524-70-7, is a conjugate of main chain and side chain.

Abbreviated as Asp-Lys-Ile-Gln-Lys(Linker-Glu-C20)-Ala, it contains 7 peptide (P7) from the main chain and the side chain, and the corresponding sequence on Tirzepatide main chain is Peptide 15 to Peptide 20.