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Query Drug：Capivasertib

Query Time：2025-04-08 14:15:34

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About the Drug

Capivasertib is used in combination with fulvestrant to treat hormone-related breast cancer.

Capivasertib is used when the cancer has progressed, spread to other parts of the body (metastatic), or after other treatments did not work or stopped working.

Capivasertib may also be used for purposes not listed in this medication guide.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Related Diseases

Extra Information on Drug and Diseases

Drug capivasertib

RXCUI: 2669967

May Treat

• Breast Neoplasms

Similar Drugs

[may_treat] Breast Neoplasms

Source MEDRT

• tamoxifen

• testolactone

• testosterone

• eribulin

• thiotepa

• vinblastine

• gemcitabine

• pertuzumab

• palbociclib

• ribociclib

• capecitabine

• neratinib

• abemaciclib

• talazoparib

• estrogens, esterified (USP)

• alpelisib

• trastuzumab

• chlorambucil

• tucatinib

• margetuximab

• fosfestrol

• synthetic conjugated estrogens, A

• cisplatin

• exemestane

• elacestrant

• capivasertib

• inavolisib

• fulvestrant

• cyclophosphamide

• ixabepilone

• diethylstilbestrol

• polyestradiol

• quinestradol

• doxorubicin

• toremifene

• vinorelbine

• epirubicin

• carboplatin

• estradiol

• estrogens, conjugated (USP)

• estrogens

• estrone

• ethinyl estradiol

• leuprolide

• dexrazoxane

• fluorouracil

• fluoxymesterone

• lapatinib

• irinotecan

• idarubicin

• ifosfamide

• paclitaxel

• synthetic conjugated estrogens, B

• medroxyprogesterone

• megestrol

• melphalan

• aminoglutethimide

• methotrexate

• methyltestosterone

• sargramostim

• mitoxantrone

• nandrolone

• docetaxel

• letrozole

• anastrozole

• quinestrol

[Physiological Effect] Decreased Endothelial Proliferation

Source: MEDRT

• thalidomide

• verteporfin

• nintedanib

• lenvatinib

• brolucizumab

• faricimab

• capivasertib

• fruquintinib

• pazopanib

[Mechanism of Action] Serine/Threonine Kinase Inhibitors

Source MEDRT

• capivasertib

Orange Book

[Last update] 2024-12-25

Labelers

Capivasertib's Innovator is ASTRAZENECA PHARMACEUTICALS LP

Drug Products

The unique dosage forms from the innovator include：1. TABLET;ORAL.

Index	Route	Brand Name	Labeler	Approval Date	Dosage
1	TABLET;ORAL	TRUQAP	ASTRAZENECA PHARMACEUTICALS LP	Nov 16, 2023	200MG
2	TABLET;ORAL	TRUQAP	ASTRAZENECA PHARMACEUTICALS LP	Nov 16, 2023	160MG

Drug Patents

This drug still has 8 effective patents.

Patent Number	Submission Date	Expiration Date	Drug Substance Patent?	Drug Product Patent?
8809336	Dec 13, 2023	Oct 25, 2025
8101623	Dec 13, 2023	Mar 10, 2030	Y	Y
10654855	Dec 13, 2023	Oct 10, 2028
11760760	Dec 13, 2023	Oct 10, 2028
10039766	Dec 13, 2023	Apr 16, 2033
9006430	Dec 13, 2023	Oct 25, 2025		Y
10059714	Dec 13, 2023	Oct 10, 2028	Y	Y
9487525	Dec 13, 2023	Apr 16, 2033	Y	Y

Related Company's Product Pipelines

The innovator ASTRAZENECA PHARMACEUTICALS LP's portolio contains products with the following 27 API(s)： OMEPRAZOLE, TAMOXIFEN CITRATE, QUETIAPINE FUMARATE, ROFLUMILAST, OMEPRAZOLE MAGNESIUM, FULVESTRANT, FELODIPINE, ATENOLOL, OMEGA-3-CARBOXYLIC ACIDS, OLAPARIB, ESOMEPRAZOLE MAGNESIUM, OSIMERTINIB MESYLATE, ENALAPRIL MALEATE; FELODIPINE, ALBUTEROL SULFATE; BUDESONIDE, BUDESONIDE; FORMOTEROL FUMARATE, TICAGRELOR, GEFITINIB, ESOMEPRAZOLE SODIUM, SELUMETINIB SULFATE, ZOLMITRIPTAN, BUDESONIDE, ISOSORBIDE DINITRATE, SODIUM ZIRCONIUM CYCLOSILICATE, TOCAINIDE HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, FORMOTEROL FUMARATE; GLYCOPYRROLATE, CAPIVASERTIB

The above products are related to 105 diseases： Esophagitis, Zollinger-Ellison Syndrome, Stomach Ulcer, Gastroesophageal Reflux, Heartburn, Helicobacter Infections, Duodenal Ulcer, Pancreatic Neoplasms, Gynecomastia, Breast Neoplasms, Puberty, Precocious, Carcinoma, Ductal, Breast, Depressive Disorder, Major, Schizophrenia, Bipolar Disorder, Autistic Disorder, Psychotic Disorders, Pulmonary Disease, Chronic Obstructive, Esophagitis, Zollinger-Ellison Syndrome, Stomach Ulcer, Gastroesophageal Reflux, Heartburn, Helicobacter Infections, Duodenal Ulcer, Breast Neoplasms, Angina Pectoris, Variant, Hypertension, Ventricular Fibrillation, Hypertension, Tachycardia, Ventricular, Myocardial Infarction, Heart Failure, Atrial Fibrillation, Tachycardia, Supraventricular, Angina Pectoris, Atrial Flutter, Ovarian Neoplasms, Esophagitis, Zollinger-Ellison Syndrome, Stomach Ulcer, Gastroesophageal Reflux, Heartburn, Helicobacter Infections, Duodenal Ulcer, Carcinoma, Non-Small-Cell Lung, Arthritis, Rheumatoid, Bartter Syndrome, Ventricular Dysfunction, Left, Hypertension, Malignant, Hypertrophy, Left Ventricular, Heart Failure, Diabetic Nephropathies, Edema, Angina Pectoris, Variant, Hypertension, Asthma, Exercise-Induced, Asthma, Bronchial Spasm, Nasal Polyps, Inflammatory Bowel Diseases, Asthma, Rhinitis, Allergic, Perennial, Nasal Polyps, Inflammatory Bowel Diseases, Asthma, Rhinitis, Allergic, Perennial, Asthma, Exercise-Induced, Asthma, Bronchial Spasm, Stroke, Coronary Thrombosis, Myocardial Infarction, Carcinoma, Non-Small-Cell Lung, Esophagitis, Zollinger-Ellison Syndrome, Stomach Ulcer, Gastroesophageal Reflux, Heartburn, Helicobacter Infections, Duodenal Ulcer, Neurofibromatosis 1, Migraine Disorders, Nasal Polyps, Inflammatory Bowel Diseases, Asthma, Rhinitis, Allergic, Perennial, Cyanosis, Poisoning, Gastroesophageal Reflux, Heart Failure, Coronary Disease, Angina Pectoris, Esophageal Spasm, Diffuse, Hyperkalemia, Depressive Disorder, Pain, Asthma, Exercise-Induced, Asthma, Bronchial Spasm, Peptic Ulcer, Hyperhidrosis, Abnormalities, Drug-Induced, Respiratory Tract Diseases, Breast Neoplasms