Drug Briefing: Osilodrostat Views: 43 Author: Unibest Industrial Publish Time: 2025-04-29 Origin: Site
Query Drug：Osilodrostat
Query Time：2025-04-29 09:47:02
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About the Drug Osilodrostat is used in adults to treat Cushing's disease that cannot be treated with pituitary surgery.
Related Diseases Extra Information on Drug and Diseases Drug osilodrostat RXCUI: 2286252
May Treat Similar Drugs [may_treat] Cushing Syndrome Source MEDRT
[Physiological Effect] Adrenal Cortical Activity Alteration Source: MEDRT
[Mechanism of Action] Adrenal Steroid Synthesis Inhibitors Source MEDRT
[Mechanism of Action] Cytochrome P450 Inhibitors Source MEDRT
[Mechanism of Action] Cytochrome P450 2D6 Inhibitors Source DAILYMED
[Mechanism of Action] Cytochrome P450 2D6 Inhibitors Source FDASPL
[Mechanism of Action] Cytochrome P450 1A2 Inhibitors Source DAILYMED
[Mechanism of Action] Cytochrome P450 1A2 Inhibitors Source FDASPL
[Mechanism of Action] Cytochrome P450 2C19 Inhibitors Source DAILYMED
[Mechanism of Action] Cytochrome P450 2C19 Inhibitors Source FDASPL
[Mechanism of Action] Cytochrome P450 3A4 Inhibitors Source DAILYMED
[Mechanism of Action] Cytochrome P450 3A4 Inhibitors Source FDASPL
[Mechanism of Action] Cytochrome P450 3A5 Inhibitors Source DAILYMED
[Mechanism of Action] Cytochrome P450 3A5 Inhibitors Source FDASPL
[Phamacological Category] Cortisol Synthesis Inhibitor Source DAILYMED
[Phamacological Category] Cortisol Synthesis Inhibitor Source FDASPL
[Mechanism of Action] Cytochrome P450 11B1 Inhibitors Source FDASPL
[Mechanism of Action] Cytochrome P450 11B1 Inhibitors Source DAILYMED
Drug osilodrostat phosphate RXCUI: 2286253
May Treat Similar Drugs [may_treat] Cushing Syndrome Source MEDRT
[Physiological Effect] Adrenal Cortical Activity Alteration Source: MEDRT
[Mechanism of Action] Adrenal Steroid Synthesis Inhibitors Source MEDRT
[Mechanism of Action] Cytochrome P450 Inhibitors Source MEDRT
Orange Book [Last update] 2024-12-25
Labelers Osilodrostat's Innovator is RECORDATI RARE DISEASES INC
Drug Products The unique dosage forms from the innovator include：1. TABLET;ORAL.
Index Route Brand Name Labeler Approval Date Dosage 1 TABLET;ORAL ISTURISA RECORDATI RARE DISEASES INC Mar 6, 2020 EQ 10MG BASE 2 TABLET;ORAL ISTURISA RECORDATI RARE DISEASES INC Mar 6, 2020 EQ 1MG BASE 3 TABLET;ORAL ISTURISA RECORDATI RARE DISEASES INC Mar 6, 2020 EQ 5MG BASE
Drug Patents This drug still has 6 effective patents.
Patent Number Submission Date Expiration Date Drug Substance Patent? Drug Product Patent? 8609862 Apr 3, 2020 Jan 13, 2031 10143680 Apr 3, 2020 Jul 6, 2035 Y 8835646 Apr 3, 2020 Aug 23, 2026 Y Y 8314097 Apr 3, 2020 Mar 27, 2029 Y Y 9434754 Apr 3, 2020 Jan 13, 2031 Y 10709691 Aug 6, 2020 Oct 12, 2035
Related Company's Product Pipelines The innovator RECORDATI RARE DISEASES INC 's portolio contains products with the following 12 API(s)： CYSTEAMINE HYDROCHLORIDE, ETHOTOIN, IBUPROFEN LYSINE, PASIREOTIDE DIASPARTATE, MECHLORETHAMINE HYDROCHLORIDE, CARGLUMIC ACID, DACTINOMYCIN, BETAINE, INDOMETHACIN SODIUM, SUCCIMER, PASIREOTIDE PAMOATE, OSILODROSTAT PHOSPHATE
The above products are related to 48 diseases： Cystinosis, Epilepsy, Complex Partial, Seizures, Epilepsy, Tonic-Clonic, Spondylitis, Ankylosing, Arthritis, Rheumatoid, Inflammation, Gout, Arthritis, Juvenile, Menorrhagia, Fever, Osteoarthritis, Pain, Pain, Postoperative, Dysmenorrhea, Premenstrual Syndrome, Bursitis, Cushing Syndrome, Pleural Effusion, Malignant, Neoplasm Metastasis, Hodgkin Disease, Mycosis Fungoides, Hyperammonemia, Melanoma, Testicular Neoplasms, Choriocarcinoma, Sarcoma, Kaposi, Sarcoma, Ewing, Rhabdomyosarcoma, Neuroblastoma, Wilms Tumor, Soft Tissue Neoplasms, Uterine Neoplasms, Gestational Trophoblastic Disease, Retinoblastoma, Homocystinuria, Spondylitis, Ankylosing, Arthritis, Gouty, Arthritis, Rheumatoid, Inflammation, Ductus Arteriosus, Patent, Osteoarthritis, Pain, Tendinopathy, Bursitis, Lead Poisoning, Nervous System, Childhood, Cushing Syndrome, Cushing Syndrome
