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Unibest NewCo & Licensing Pipeline

Views: 53     Author: Unibest Industrial     Publish Time: 2025-05-14      Origin: Site

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ADC

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB044HER2Breast Cancer

UB126ADAM9Gastrointestinal Cancer

UB127EGFR;cMetLung Cancer

UB134mAb+Dual payloadCRC,HNSC,PAAD,NSCLC,etc.

UB135Bi-functional mAb+ Dual payloadSolid tumors

UB137Undisclosed (mAb+Dual-payload)Solid tumors

UB138Undisclosed (BsAb+Dual-payload)Solid tumors

UB136BsAb+Dual-payloadSolid tumors

UB032Nectin-4/Trop2Bladder cancer; cervical cancer; lung cancer

UB031cMet/HER2Pancreatic cancer; lung cancer; gastrointestinal cancer; renal cancer

UB022HER2;Trop2Breast cancer; cervical cancer; gastric cancer

Antibody

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB053PDL1; 4-1BBExtrapulmonary Neuroendocrine Carcinomas

UB056PDL1; 4-1BBNSQ-NSCLC; NSCLC; biliary cancer; solid tumor (+ radiotherapy; +/- VEGF)

UB055PDL1; 4-1BBExtrapulmonary Neuroendocrine Carcinomas; NSCLC (+ radiotherapy)

UB054PDL1; 4-1BBNSCLC; biliary cancer; solid tumor

UB014EGFR; CD3Metastatic breast cancer; gastric cancer

UB013LAG3Solid tumors and lymphoma; autoimmune

UB149AβAlzheimer's Disease

UB017IL-12 prodrugSolid tumors

UB015EGFR; CD3 (enzyme-controlled)Solid tumors

UB060MUC16; CD3Ovarian cancer; cervical cancer; solid tumor

UB058GPRC5D; CD3MM

UB061MUC16; CD3Solid tumor (US)

UB023PD-L1; VEGFLung cancer; breast cancer

UB041HERV-K Env-TMAll cancer

UB021CD3 bispecific antibody prodrugSolid tumors

UB019GPC3; CD3Hepatocellular carcinoma

UB018RORI; CD3Lymphoma; breast cancer

UB020PD-1/IL-15 cytokine antibody conjudgateSolid tumors

UB059GPRC5D; CD3MM (US)

UB057PDL1; 4-1BBSolid tumor (US)

CGT

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB038(siRNA)NMSC

UB084(Oncolytic virus)Metastatic refractory tumors, including squamous cell carcinoma of the head and neck, lung cancer, ovarian cancer, sarcoma, triple-negative breast cancer, and other sensitive tumors.
About
UB098HBVHepatocelluar Carcinoma

UB099HBVCholangio-carcinoma

UB139PCSK9 (siRNA)Hypercholesteremia

UB144(siRNA)Solid tumors

UB145Factor XI (siRNA)Anticoagulation, Stroke

UB039(siRNA)Focal Fat Reduction

UB140PCSK9 (siRNA)Hypercholesteremia

UB085(Oncolytic virus)Metastatic refractory tumors, including squamous cell carcinoma of the head and neck, lung cancer, ovarian cancer, sarcoma, triple-negative breast cancer, and other sensitive tumors. （US）
About
UB100HBVChronic Hepatitis B

UB101HPVCervical, Head & Neck Cancer

UB146ApoC3 (siRNA)Hypertriglyceridemia

UB102EBVSolid tumor

UB103(iPSC)Solid tumor

UB089IL4R (siRNA)Atopic dermatitis

UB090Calcineurin/Fn14 (siRNA)Organ transplant; autoimmune

UB092(siRNA)Age-related macular degeneration

UB095(siRNA)Nephrotic syndrome

UB096SGLT2 (siRNA)Type 2 Diabetes; ghout

UB097(siRNA)Melanoma

UB091Glucosylceramide synthase (siRNA)Gaucher/Fabry

UB093Renin / AGTHypertension

UB094FcRn (siRNA)Myasthenia gravis

Peptide

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB011GLP-1 RDiabetes

UB080GLP-1Obesity

UB047GLP-1;GCGObesity

UB045GLP-1Type 2 Diabetes (US)

UB081GLP-1MASH

UB012GLP-1 RObesity

UB049μ opioid receptorOIC

UB048GLP-1;GCGMASH (US)

UB046GLP-1Type 2 Diabetes + SGLT-2

UB050GCGRCongenital hyperinsulinism

UB104GLP-1 (Oromucosal)Diabetes; Obesity
About
UB051GLP-1; GIPType 2 Diabetes; Obesity; MASH

UB052GLP-1R; GIPR; GCGRType 2 Diabetes; Obesity; MASH

UB010GLP-1 RDiabetes

Small Molecule

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB082F protein (RSV)RSV

UB075Urat1Hyperuricemia; ghout

UB073PI3KδPeripheral T cell lymphoma

UB068JAK1 (oral)Ankylosing spondylitis

UB067JAK1 (topical)Moderate to severe atopic dermatitis

UB066P2Y12RACS; Ischemic stroke; peripheral arterial disease

UB065P2Y12RACS

UB072FLT3; FGFRAML

UB063HBV CaspidCHB

UB166
Post operative pain

UB071PDL1Solid tumor

UB164
Post operative pain

UB0425-HT; DAASD

UB074PI3KδPeripheral T cell lymphoma (US)

UB024KV1.3 (Topical)Atopic dermatitis
About
UB077Kras G12CLung cancer, Colorectal cancer, pancreatic cancer haboring G12C mutation

UB064TEADOncology

UB069RIPK1Peripheral arterial diseases; primary biliary cirrhosis

UB083F protein (RSV)RSV prevention

UB076pan-KRASOncology

UB147Keratin, PlasminMelasma

UB062KCNQ2/3Epilepsy

UB078HIPK2Fibrosis

UB027mTORC2Neuroendocrine tumors; lung cancer; breast cancer

UB028FXIaThrombus

UB176KV1.3 (Topical)Psoriasis
About
UB026PI3K-Akt-mTOR pathwayMelanoma; esophageal cancer, colorectal cancer

UB029KV1.3 (Oral)Inflammatory bowel disease
About
UB030cMyc pathwayGynecological tumors

UB177KV1.3 (Oral)Atopic dermatitis
About
UB167TRPV1Neuropathic pain

UB148Androgen receptorAcne

UB165
Post operative pain

UB181GPCRCOPD

UB180GPCROcular inflammatory diseases

UB179GPCRDiabetic retinopathy; age related macular degeneration

UB178KV1.3 (Topical)Alopecia
About
UB125GABAA ReceptorEpilepsy

UB040Multiple targets; immunostimulantsAll cancer

UB043Agmatinase, Imidazoline Rc, NMDA RcASD

UB070pan-RAS (on)Solid tumor

UB182Ion channel inhibitorPruritus

UB183Ion channel inhibitorDiabetic nephropathy

Targeted Protein Degradation

CodeTargetIndicationPreclinicalPh IPh IIPh IIINDA/BLADetail
UB025cMycPancreatic cancer
About

Last Updated: 2025-05-30

NewCo license out antibody small molecule ADC recombinant protein CGT targeted protein degradation